Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling
The Kappa Opioid Receptor: From Addiction to Depression, and Back | Semantic Scholar
Endogenous opioid system dysregulation in depression: implications for new therapeutic approaches | Molecular Psychiatry
Frontiers Publishing Partnerships | Mechanisms Underlying the Anti-Suicidal Treatment Potential of Buprenorphine
Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects
Opioid receptors: distinct roles in mood disorders | Semantic Scholar
Frontiers | Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain
Dynorphin, stress, and depression | Semantic Scholar
Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor | Journal of Medicinal Chemistry
IJMS | Free Full-Text | Stress-Induced Changes in the Endogenous Opioid System Cause Dysfunction of Pain and Emotion Regulation
Frontiers | The Role of the Kappa Opioid System in Comorbid Pain and Psychiatric Disorders: Function and Implications
Role of kappa-opioid receptors in stress and anxiety-related behavior. - Abstract - Europe PMC
Brain Sciences | Free Full-Text | Shared Mechanisms of GABAergic and Opioidergic Transmission Regulate Corticolimbic Reward Systems and Cognitive Aspects of Motivational Behaviors
Development of κ Opioid Receptor Antagonists | Journal of Medicinal Chemistry
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect
Opioid receptor modulation of neural circuits in depression: What can be learned from preclinical data? - ScienceDirect
Scientists Take a Big Step toward Building a Better Opioid | Newsroom
Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment - ScienceDirect
κ-opioid receptor - Wikipedia
Frontiers | A Trigger for Opioid Misuse: Chronic Pain and Stress Dysregulate the Mesolimbic Pathway and Kappa Opioid System
Frontiers | Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain
