Home

Σενάριο ανάβω φωτιά Πολύ θυμωμένος kappa opioid receptor activates p38 Διστάζω θερίζω Δούρειος ίππος

Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands:  Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience
Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience

Reactive oxygen species (ROS) generation is stimulated by κ opioid receptor  activation through phosphorylated c-Jun N-terminal kinase and inhibited by  p38 mitogen-activated protein kinase (MAPK) activation - ScienceDirect
Reactive oxygen species (ROS) generation is stimulated by κ opioid receptor activation through phosphorylated c-Jun N-terminal kinase and inhibited by p38 mitogen-activated protein kinase (MAPK) activation - ScienceDirect

Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or  approach-avoidance behavior occur differentially across the nucleus  accumbens shell rostro-caudal axis - ScienceDirect
Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis - ScienceDirect

Dopaminergic cellular and circuit contributions to kappa opioid receptor  mediated aversion
Dopaminergic cellular and circuit contributions to kappa opioid receptor mediated aversion

Dopaminergic Cellular and Circuit Contributions to Kappa Opioid Receptor  Mediated Aversion
Dopaminergic Cellular and Circuit Contributions to Kappa Opioid Receptor Mediated Aversion

RETRACTED ARTICLE: Down-regulation of kappa opioid receptor promotes ESCC  proliferation, invasion and metastasis via the PDK1-AKT signaling pathway |  Cell Communication and Signaling | Full Text
RETRACTED ARTICLE: Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway | Cell Communication and Signaling | Full Text

Kappa opioid receptor signaling in the brain: Circuitry and implications  for treatment | Semantic Scholar
Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment | Semantic Scholar

Kappa opioid receptor (KOR) activation study. A): G protein activation... |  Download Scientific Diagram
Kappa opioid receptor (KOR) activation study. A): G protein activation... | Download Scientific Diagram

Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA  Dopamine Neurons | Journal of Neuroscience
Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons | Journal of Neuroscience

Nalfurafine is a G-protein biased agonist having significantly greater bias  at the human than rodent form of the kappa opioid receptor - ScienceDirect
Nalfurafine is a G-protein biased agonist having significantly greater bias at the human than rodent form of the kappa opioid receptor - ScienceDirect

Opioids As Modulators of Cell Death and Survival—Unraveling Mechanisms and  Revealing New Indications | Pharmacological Reviews
Opioids As Modulators of Cell Death and Survival—Unraveling Mechanisms and Revealing New Indications | Pharmacological Reviews

Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and  Arrestin-dependent in Neurons and Astrocytes* - Journal of Biological  Chemistry
Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and Arrestin-dependent in Neurons and Astrocytes* - Journal of Biological Chemistry

Frontiers | Opioid Receptor-Mediated Regulation of Neurotransmission in the  Brain
Frontiers | Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain

Molecular Mechanisms of Opioid Receptor-dependent Signaling and Behavior
Molecular Mechanisms of Opioid Receptor-dependent Signaling and Behavior

Kinase cascades and ligand-directed signaling at the kappa opioid receptor.  - Abstract - Europe PMC
Kinase cascades and ligand-directed signaling at the kappa opioid receptor. - Abstract - Europe PMC

Frontiers | Mu Opioid Receptor Heterodimers Emerge as Novel Therapeutic  Targets: Recent Progress and Future Perspective
Frontiers | Mu Opioid Receptor Heterodimers Emerge as Novel Therapeutic Targets: Recent Progress and Future Perspective

IJMS | Free Full-Text | Is p38 MAPK Associated to Drugs of Abuse-Induced  Abnormal Behaviors?
IJMS | Free Full-Text | Is p38 MAPK Associated to Drugs of Abuse-Induced Abnormal Behaviors?

Agonist-induced phosphorylation bar code and differential post-activation  signaling of the delta opioid receptor revealed by phosphosite-specific  antibodies | Scientific Reports
Agonist-induced phosphorylation bar code and differential post-activation signaling of the delta opioid receptor revealed by phosphosite-specific antibodies | Scientific Reports

Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical  Role of the Dynorphin/Kappa Opioid Receptor System
Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical Role of the Dynorphin/Kappa Opioid Receptor System

Constitutive activation of kappa opioid receptors at ventral tegmental area  inhibitory synapses following acute stress | eLife
Constitutive activation of kappa opioid receptors at ventral tegmental area inhibitory synapses following acute stress | eLife

κ-opioid receptor - Wikipedia
κ-opioid receptor - Wikipedia

Biased ligands at opioid receptors: Current status and future directions |  Science Signaling
Biased ligands at opioid receptors: Current status and future directions | Science Signaling

Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for  the Development of Potential Treatments of Pain with Reduced Side Effects
Molecules | Free Full-Text | Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects

Frontiers | Advances in Achieving Opioid Analgesia Without Side Effects
Frontiers | Advances in Achieving Opioid Analgesia Without Side Effects

Constitutive activation of kappa opioid receptors at ventral tegmental area  inhibitory synapses following acute stress | eLife
Constitutive activation of kappa opioid receptors at ventral tegmental area inhibitory synapses following acute stress | eLife

Biased agonists of the kappa opioid receptor suppress pain and itch without  causing sedation or dysphoria | Science Signaling
Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling

Opioids in cancer: The κ‑opioid receptor (Review)
Opioids in cancer: The κ‑opioid receptor (Review)

Kappa Receptors – Opioid Peptides
Kappa Receptors – Opioid Peptides